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Where Beauty and Wellness Meet

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We help you feel at home in your body again

At Southern Serenity & Co, we specialize in personalized aesthetic and wellness treatments designed to help you feel your best—inside and out. From hormone optimization and weight loss to facial balancing, body sculpting, and beyond, we support your goals with a results-focused, medically guided approach.

HOW WE DO IT

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Wellness
A woman with closed eyes receiving a cosmetic or medical injection in her forehead from a healthcare professional wearing pink gloves.
Aesthetics
A woman receiving a facial treatment from an esthetician in a spa or skincare clinic.
Spa
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Testimonials

  • "Just when I think Southern Serinity can’t get any better, they prove me wrong by adding Anna to their team!! Cari & Julia have been working literal magic on my skin for a while now, but I had my first massage with Anna this week and it was 10/10. She is so kind and made me feel so comfortable from the moment I walked into the salon. Her massage room is so cozy, and the relaxation was next level. Not to mention my body feels GREAT! Highly recommend going to see her when you’re ready for your next massage. The entire experience was incredible, and I can’t wait to go see her again! Southern Serinity is truly the best in town and if you’re not going to see them for all things Med Spa & Massage, you’re just not doing it right. "

    ★★★★★ Christina H.

  • "I absolutely love Southern Serenity!! I’ve received several different treatments here from weight loss to massage! Julia is totally awesome. She’s managed my weight loss and has also given me facial injections. Faith has also given me a wonderful facial and treatment! Everyone is so nice from the minute you walk in the door. I recently got an amazing massage by Anna and will be getting many more. I highly recommend Southern Serenity for whatever you need ❤️"

    ★★★★★ Lori E.

  • "Southern Serenity Med Spa is amazing! I’ve lost over 100 lbs with their weight loss shots, love their facials, and buy all my skincare products here. Anna gives incredible massages, and Julia is a pro with fillers and toxins. Kali makes the whole place feel like family. Which is why we love everyone at Southern Serenity!"

    ★★★★★ Jessica L.

  • "Since the first appointment I made with Southern Serenity Spa, I have been a fan. They have assisted me in my weight loss journey, as well as, my aging gracefully journey and I couldn’t be happier. The staff is extremely professional, friendly, and accommodating. Make yourself an appointment, you won’t be disappointed!"

    ★★★★★ Jennifer W.

  • "The staff here truly cares for your well-being. I could not recommend coming here more. They are kind, caring, and very helpful! Julia has become my new Primary, and I could not recommend her more. My experience here has been nothing short of amazing!"

    ★★★★★ Gabby H.

  • “I am beyond satisfied with the service provided by Simply Southern! I’ve had multiple services including IV therapy & Botox. All services have been a 10 out of 10! They are very knowledgeable and friendly. I definitely recommend their services.”

    ★★★★★ Lynn

A woman with dark hair wearing pink gloves is giving a facial treatment to a patient lying down on a treatment bed.

Our Location

Southern Serenity is more than a med spa—it’s a space we’ve built to welcome you, care for you, and support your journey to feeling your best.

Visit Us

1399 Jenks Ave Suite H,
Panama City, FL 32401

(850) 814-0786

Confidence Begins Here

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