Medical Weight Loss
Semaglutide
Semaglutide is a weight loss peptide that mimics GLP-1, a hormone that:
Increases insulin secretion (when blood sugar/glucose is high)
Reduces glucagon secretion
Slows gastric emptying (helps you feel full longer)
Acts on the brain to reduce appetite
Type 2 Diabetes: Lowers blood sugar (HbA1c reduction ~1–1.5%)
Weight loss: Promotes significant weight loss (up to 10–15% of body weight in many patients)
Cardiovascular benefits: Reduces cardiovascular risk in people with type 2 diabetes
Benefits of Semaglutide
Tirzepatide
Tirzepatide is a weight loss peptide that mimics both GIP and GLP-1, and does the following:
Increases insulin secretion (when blood sugar/glucose is high).
Decreases glucagon (lowers glucose release from the liver).
Slows gastric emptying, which leads to prolonged fullness.
Reduces appetite via central effects on the brain.
Type 2 diabetes: lowers HbA1c more than semaglutide in head-to-head trials.
Weight loss: in clinical studies, patients lost 15–22% of body weight (often greater than with semaglutide).
Cardiovascular benefits: ongoing studies suggest reduced risk of major events in diabetics, but long-term data are still being collected.